Research

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KLC4 shapes axon arbors during development and mediates adult behavior

Elizabeth M Haynes, Korri H Burnett, Jiaye He, Marcel W Jean-Pierre, Martin Jarzyna, Kevin W Eliceiri, Jan Huisken, Mary C Halloran

eLife  ·  12 Oct 2022  ·  doi:10.7554/eLife.74270

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2022

KLC4 shapes axon arbors during development and mediates adult behavior

Elizabeth M Haynes, Korri H Burnett, Jiaye He, Marcel W Jean-Pierre, Martin Jarzyna, Kevin W Eliceiri, Jan Huisken, Mary C Halloran

eLife  ·  12 Oct 2022  ·  doi:10.7554/eLife.74270

2021

KLC4 shapes axon arbors during development and mediates adult behavior

Elizabeth M. Haynes, Korri H. Burnett, Jiaye He, Marcel Jean-Pierre, Martin Jarzyna, Kevin W. Eliceiri, Jan Huisken, Mary C. Halloran

Cold Spring Harbor Laboratory  ·  26 Sep 2021  ·  doi:10.1101/2021.09.26.461872

2017

The Kinesin Adaptor Calsyntenin-1 Organizes Microtubule Polarity and Regulates Dynamics during Sensory Axon Arbor Development

Tristan J. Lee, Jacob W. Lee, Elizabeth M. Haynes, Kevin W. Eliceiri, Mary C. Halloran

Frontiers in Cellular Neuroscience  ·  20 Apr 2017  ·  doi:10.3389/fncel.2017.00107

2016

Tropomyosin Promotes Lamellipodial Persistence by Collaborating with Arp2/3 at the Leading Edge

Simon Brayford, Nicole S. Bryce, Galina Schevzov, Elizabeth M. Haynes, James E. Bear, Edna C. Hardeman, Peter W. Gunning

Current Biology  ·  01 May 2016  ·  doi:10.1016/j.cub.2016.03.028

Lamellipodia are critical for haptotactic sensing and response

Samantha J. King, Sreeja B. Asokan, Elizabeth M. Haynes, Seth P. Zimmerman, Jeremy D. Rotty, …, Maddy Parsons, Norman E. Sharpless, Brian Kuhlman, Jason M. Haugh, James E. Bear

Journal of Cell Science  ·  01 Jan 2016  ·  doi:10.1242/jcs.184507

2015

GMFβ controls branched actin content and lamellipodial retraction in fibroblasts

Elizabeth M. Haynes, Sreeja B. Asokan, Samantha J. King, Heath E. Johnson, Jason M. Haugh, James E. Bear

Journal of Cell Biology  ·  22 Jun 2015  ·  doi:10.1083/jcb.201501094

Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

Jeremy D. Rotty, Congying Wu, Elizabeth M. Haynes, Cristian Suarez, Jonathan D. Winkelman, Heath E. Johnson, Jason M. Haugh, David R. Kovar, James E. Bear

Developmental Cell  ·  01 Jan 2015  ·  doi:10.1016/j.devcel.2014.10.026

2013

Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling

Congying Wu, Elizabeth M. Haynes, Sreeja B. Asokan, Jeremy M. Simon, Norman E. Sharpless, Albert S. Baldwin, Ian J. Davis, Gary L. Johnson, James E. Bear

Journal of Cell Biology  ·  16 Dec 2013  ·  doi:10.1083/jcb.201306032

2012

Arp2/3 Is Critical for Lamellipodia and Response to Extracellular Matrix Cues but Is Dispensable for Chemotaxis

Congying Wu, Sreeja B. Asokan, Matthew E. Berginski, Elizabeth M. Haynes, Norman E. Sharpless, Jack D. Griffith, Shawn M. Gomez, James E. Bear

Cell  ·  01 Mar 2012  ·  doi:10.1016/j.cell.2011.12.034